Many advanced cancers, such as melanoma, evade the immune system by exploiting negative feedback mechanisms.Immune checkpoint inhibitor (ICI) therapy dramatically enhances immune surveillance and has revolutionized treatment of advanced melanoma.However, ICI therapy is also associated with multiple cutaneous adverse events.We describe a patient tre
Abstract Background RNA interference (RNAi) is a tool for studying gene function and has emerged as a promising eco-friendly alternative to chemical pesticides.RNAi relies on delivering double-stranded Teflon Sheets RNA (dsRNA), which is processed into small interfering RNA (siRNA) to silence genes.However, so far, knowledge and tools for optimizin
The downstreaming option to provide added value to local industries, especially developing countries in the Global Value Chain (GVC) era as a way to ORG KIDNEY BEANS increase competitiveness and seizing global markets, is inevitable.This paper focus on the analysis of the developments and limitations faced in the implementation of the Strategic Pol
Abstract The growth in the number of immigrants ENERGIZER LEMONLIME in Brazil has stimulated reflections on how these people represent and signify aspects of the new context in which they are situated.This study aimed to trace social representations of Haitian immigrants about work in Brazil.Fifteen Haitians from a city in southern Brazil participa